The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
BRCA1 (Phospho-Ser1457) Antibody
Synonyms
BRCA1; Breast cancer type 1 susceptibility protein; familial breast/ovarian cancer gene 1
Immunogen
The antiserum was produced against synthesized phospho-peptide derived from human BRCA1 around the phosphorylation site of Ser1457.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
BRCA1 (Phospho-Ser1457) Antibody detects endogenous levels of BRCA1 only when phosphorylated at Ser1457.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (Phospho-without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
BRCA1
Database Links
Gene ID: 672 Swiss-Prot #: P38398
OMIM #: 113705/114480 Unigene #: Hs.194143
Target Modification
Phospho
Modification Sites
H:S1457
Application Images
Image 1
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using BRCA1 (Phospho-Ser1457) Antibody
Image 2
Western blot analysis of lysates from 293 cells treated with epo 20U/ml 15', using BRCA1 (Phospho-Ser1457) Antibody.