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Sigma-Aldrich/Monoamine Oxidase Activity Assay Kit/MAK136-1KT/1KT
  • Sigma-Aldrich/Monoamine Oxidase Activity Assay Kit/MAK136-1KT/1KT

Sigma-Aldrich/Monoamine Oxidase Activity Assay Kit/MAK136-1KT/1KT

價(jià)格: ¥2774.00 市場(chǎng)價(jià): 3606.20

貨號(hào): MAK136-1KT
品牌: Sigma-Aldrich
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    • Synonym: MAO Assay Kit
      • Popular Documents:  Bulletin (PDF)  |  Specification Sheet (PDF)  

      Properties:

      Related Categories Blood and Urine Chemistry Assay Kits, Cell Biology, Enzymatic Activity Assay Kits, Enzymatic Kits for the Quantitation of Nutrients and Metabolites, Metabolism Assay Kits A-Z,
      More...
      usage   sufficient for 100 fluorometric?tests
      storage temp.   −20°C
      Gene Information   human ... MAOA(4128), MAOB(4129)
      mouse ... MAOA(17161), MAOB(109731)
      rat ... MAOA(29253), MAOB(25750)

      Description:

      Features and Benefits

      Compatible with high-throughput handling systems.

      General description

      Monoamine oxidases (MAO, EC 1.4.3.4) are a family of mitochondrial enzymes that catalyze the oxidative deamination of monoamines. In mammals, MAO consists of two isoenzymes, MAO-A and MAO-B. MAO dysfunction is thought to be responsible for a number of neurological disorders. Unusually high or low levels of MAO in the body have been associated with depression, schizophrenia, substance abuse, attention deficit disorder, migraines, and irregular sexual maturation. MAO inhibitors are one of the major classes of drug prescribed for the treatment of depression.

      The Monoamine Oxidase Assay Kit provides a convenient fluorimetric means to measure MAO enzyme activity in biological samples. In the assay, MAO reacts with p-tyramine, a substrate for both MAO-A and MAO-B, resulting in the formation of H2O2, which is determined by a fluorimetric method (λex = 530/λem = 585 nm). The assay is simple, sensitive, stable, and high-throughput adaptable. Unit definition: one unit of MAO catalyzes the formation of 1 μmole of H2O2 per minute under the assay conditions.

      Suitability

      Suitable for the determination of MAO activity in biological samples and for the screening of MAO inhibitors. Can determine either MAO-A, MAO-B or both MAO-A and MAO-B activity.

      Safety:

      Symbol 
      GHS05  GHS05
      Signal word 
      Danger
      Hazard statements 
      H315-H318
      Precautionary statements 
      P280-P305 + P351 + P338
      RIDADR 
      NONH for all modes of transport
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