The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
ADAM 17 (Cleaved-Arg215) Antibody
Synonyms
ADA17; ADAM 17; CD156b antigen; CSVP; TACE; TNF-alpha convertase; TNF-alpha-converting enzyme; a disintegrin and metalloproteinase domain 17; snake venom-like protease
Immunogen
The antiserum was produced against synthesized peptide derived from human ADAM 17.
Immunogen Range
196-245
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:20000
Specificity
ADAM 17 (Cleaved-Arg215) Antibody detects endogenous levels of fragment of activated ADAM 17 resulting from cleavage adjacent to Arg215.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
ADAM17
Database Links
Gene ID: 6868 Swiss-Prot #: P78536
OMIM #: 603639 Unigene #: Hs.404914
Target Modification
Cleaved
Modification Sites
Application Images
Image 1
Western blot analysis of lysates from rat liver cells, using ADAM 17 (Cleaved-Arg215) Antibody. The lane on the right is blocked with the synthesized peptide.