The antiserum was produced against synthesized peptide derived from human Caspase-1 (Cleaved-Asp210).
Immunogen Range
161-210
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
Specificity
Caspase -1 (Cleaved-Asp210) Antibody detects endogenous levels of fragment of activated Caspase-1 resulting from cleavage adjacent to Asp210.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
CASP1
Database Links
Gene ID: 834 Swiss-Prot #: P29466
OMIM #: 147678 Unigene #: Hs.2490
Target Modification
Cleaved
Modification Sites
Asp210
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Caspase-1 (Cleaved-Asp210) Antibody. The picture on the right is blocked with the synthesized peptide.
Image 2
Western blot analysis of extracts from K562 cells, and HepG2 cells treated with adriamycin, using Caspase 1 (Cleaved-Asp210) antibody (#L0114). The lane on the right is blocked with the synthesized peptide.