The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
Ku70 (Acetyl-Lys331) Antibody
Synonyms
XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6
Immunogen
The antiserum was produced against synthesized Acetyl-peptide derived from human Ku70 around the Acetylation site of Lys331.
Immunogen Range
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 ELISA: 1:10000
Specificity
Ku70 (Acetyl-Lys331) Antibody detects endogenous levels of Ku70 protein only when acetylated at Lys331.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
XRCC6
Database Links
Gene ID: 2547 Swiss-Prot #: P12956
OMIM #: 152690 Unigene #: Hs.292493
Target Modification
Acetyl
Modification Sites
H:K331, M:K329, R:K329
Application Images
Image 1
Western blot analysis of lysate from 4T1 cells, using Ku70 (Acetyl-Lys331) Antibody.