BackgroundInformation | Aquaporin-4(AQP-4)isalsoknownasMercurial-insensitivewaterchannel.AQP-4isanosmoreceptorwhichregulatesbodywaterbalanceandmediateswaterflowwithinthecentralnervoussystem.Itisexpressedpredominantlyinthematurebrain,butalsointheeye,kidney,intestineandlung.AQP-4isamulti-passmembraneproteinthatispartofacomplexalongwithMLC1,TRPV4,HEPACAMandATP1B1. |