Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | TrkB(Phospho-Tyr706+Tyr707)Antibody |
Synonyms | BDNF/NT-3growthfactorsreceptorprecursor;GP145-TrkB;GP145-TrkB/GP95-TrkB;NTRK2;Trk-B;TrkBtyrosinekinase;kinaseTrkB |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanTrkBaroundthephosphorylationsiteofTyr706andTyr707. |
ImmunogenRange | 676-725 |
Clonality | Polyclonal |
ApplicationDilutions | IHC:1:50~1:100ELISA:1:10000 |
Specificity | TrkB(Phospho-Tyr706+Tyr707)AntibodydetectsendogenouslevelsofTrkBonlywhenphosphorylatedatTyr706andTyr707. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | NTRK2 |
DatabaseLinks | GeneID: 4915 Swiss-Prot#: Q16620 OMIM#: 600456 Unigene#: Hs.494312/Hs.712776 |
TargetModification | Phospho |
ModificationSites | H:Y706+Y707M:Y705+Y706R:Y705+Y706 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingTrkB(Phospho-Tyr706+Tyr707)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |