The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
SMC1 (Phospho-Ser957) Antibody
Synonyms
Chromosome segregation protein SmcB; DXS423E; KIAA0178; SB1.8/DXS423E protein; SM1A; SMC1A; SMC1L1; SMC1alpha protein; Sb1.8; Structural maintenance of chromosome 1-like 1 protein
Immunogen
The antiserum was produced against synthesized peptide derived from human SMC1 around the phosphorylation site of Ser957.
Immunogen Range
931-980
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000
Specificity
SMC1 (Phospho-Ser957) Antibody detects endogenous levels of SMC1 only when phosphorylated at Ser957.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
SMC1A
Database Links
Gene ID: 8243 Swiss-Prot #: Q14683
OMIM #: 300040/300590 Unigene #: Hs.211602
Target Modification
Phospho
Modification Sites
H:S957 M:S957
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using SMC1 (Phospho-Ser957) Antibody. The picture on the right is blocked with the phospho peptide.
Image 2
Western blot analysis of lysates from HUVEC cells treated with EGF 200ng/ml 5'/HeLa cells treated with EGF 200ng/ml 15', using SMC1 (Phospho-Ser957) Antibody. The lane on the right is blocked with the phospho peptide.