Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | c-Kit(Phospho-Tyr721)Antibody |
Synonyms | SCFR;Proto-oncogenetyrosine-proteinkinaseKit;c-kit;CD117antigen |
Immunogen | Theantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanc-KitaroundthephosphorylationsiteofTyr721. |
ImmunogenRange | 688-737 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000ELISA:1:10000 |
Specificity | c-Kit(Phospho-Tyr721)Antibodydetectsendogenouslevelsofc-KitonlywhenphosphorylatedatTyr721. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | KIT |
DatabaseLinks | GeneID: 3815 Swiss-Prot#: P10721 OMIM#: 164920/172800/273300/606764 Unigene#: Hs.479754 |
TargetModification | Phospho |
ModificationSites | H:Y721M:Y719R:Y722 |
ApplicationImages |
Image1 | WesternblotanalysisoflysatesfromHepG2cellstreatedwithEGF200ng/ml30",usingc-Kit(Phospho-Tyr721)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |