The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
CD45 (Phospho-Ser1007) Antibody
Synonyms
L-CA; Leukocyte common antigen precursor; Leukocyte common antigen variant 4 precursor; LY-5; Lymphocyte common antigen Ly-5; PTPRC; T200
Immunogen
The antiserum was produced against synthesized peptide derived from human CD45 around the phosphorylation site of Ser1007.
Immunogen Range
981-1030
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IF: 1:100~1:500 ELISA: 1:5000
Specificity
CD45 (Phospho-Ser1007) Antibody detects endogenous levels of CD45 only when phosphorylated at Ser1007.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
PTPRC
Database Links
Gene ID: 5788 Swiss-Prot #: P08575
OMIM #: 126200/151460/608971 Unigene #: Hs.654514
Target Modification
Phospho
Modification Sites
H:S1007 M:S996
R:S960
Application Images
Image 1
Immunofluorescence analysis of HeLa cells, using CD45 (Phospho-Ser1007) Antibody. The picture on the right is blocked with the phospho peptide.
Image 2
Western blot analysis of lysates from HeLa cells treated with TNF 20ng/ml 15', using CD45 (Phospho-Ser1007) Antibody. The lane on the right is blocked with the phospho peptide.