The product is for research use only, not for use in diagnostic or therapeutic procedures
Product Name
Ku70 (Phospho-Ser5) Antibody
Synonyms
X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; X-ray repair complementing defective repair in Chinese hamster cells 6; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subu
Immunogen
The antiserum was produced against synthesized peptide derived from human Ku70 around the phosphorylation site of Ser5.
Immunogen Range
Jan-50
Clonality
Polyclonal
Application Dilutions
WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:1000
Specificity
Ku70 (Phospho-Ser5) Antibody detects endogenous levels of Ku70 only when phosphorylated at Ser5.
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Physical Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability
Stable at -20°C for at least 1 year.
NCBI Gene Symbol
XRCC6
Database Links
Gene ID: 2547 Swiss-Prot #: P12956
OMIM #: 152690 Unigene #: Hs.292493
Target Modification
Phospho
Modification Sites
H:S5 M:S6
Application Images
Image 1
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using Ku70 (Phospho-Ser5) Antibody. The picture on the right is blocked with the phospho peptide.
Image 2
Western blot analysis of lysates from HeLa cells, using Ku70 (Phospho-Ser5) Antibody. The lane on the right is blocked with the phospho peptide.