Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | Lyn(Phospho-Tyr507)Antibody |
Synonyms | ONCOGENELYN;v-yes-1Yamaguchisarcomaviralrelatedoncogenehomolog |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanLynaroundthephosphorylationsiteofTyr507. |
ImmunogenRange | 463-512 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:1000 |
Specificity | Lyn(Phospho-Tyr507)AntibodydetectsendogenouslevelsofLynonlywhenphosphorylatedatTyr507. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | LYN |
DatabaseLinks | GeneID: 4067 Swiss-Prot#: P07948 OMIM#: 165120 Unigene#: Hs.699154 |
TargetModification | Phospho |
ModificationSites | H:Y507M:Y507R:Y508 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbrain,usingLyn(Phospho-Tyr507)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image2 | WesternblotanalysisoflysatesfromK562cellstreatedwithH2O2100uM30",usingLyn(Phospho-Tyr507)Antibody.Thelaneontherightisblockedwiththephosphopeptide. |