AlternateNames | - S100calciumbindingproteinA4
- S100calcium-bindingproteinA4
- fibroblast-specificprotein-1
- leukemiamultidrugresistanceassociatedprotein
- S100calciumbindingproteinA4(calciumprotein,calvasculin,metastasin,murineplacentalhomolog)
- malignanttransformationsuppression1
- S100calcium-bindingproteinA4(calciumprotein,calvasculin,metastasin,murineplacentalhomolog)
- Metastasin
- ProteinMts1
- Placentalcalcium-bindingprotein
- Calvasculin
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BackgroundInformation | Fibroblast-specificprotein-1(FSP1)/S100A4isacytoplasmiccalcium-bindingproteinbelongingtotheS100superfamilyofwhichatleast21membershavebeenidentifiedsofar.ResearchersbelievethatFSP1/S1004Aishighlyexpressedinfibroblasts(Iwanoetal.,2001;Strutzetal.,1995),inepithelialandendothelialcellsundergoingepithelial-mesenchymaltransition(EMT)(Iwanoetal.,2002;ZeisbergandNeilson,2009),andepithelialcancercellsthatcompleteatransitiontoametastaticphenotype(Xueetal.,2003). |