當(dāng)前位置 ： Millipore >>> Millipore/06-340 | Anti-Myc Antibody/06-340/100 µg
Millipore/06-340 | Anti-Myc Antibody/06-340/100 µg
  • Millipore/06-340 | Anti-Myc Antibody/06-340/100 µg

Millipore/06-340 | Anti-Myc Antibody/06-340/100 µg

價(jià)格: 試用 市場價(jià): 0.00
貨號: 06-340
品牌: Millipore
規(guī)格
數(shù)量
庫存(0)
特別 提示
代購產(chǎn)品：無質(zhì)量問題不接受退換貨，下單前請仔細(xì)核對信息。
下單后請及時(shí)聯(lián)系客服核對商品價(jià)格，訂單生效后再付款。
資深產(chǎn)品顧問
咨詢顧問

全國免費(fèi)服務(wù)熱線

4000-520-616

  • 自營商城 一站式服務(wù)
  • 廠家直采 剔除溢價(jià)
  • 品質(zhì)甄選 正品保證
  • 嚴(yán)控流程 只做188精品
  • 極速物流 如約送貨
  • 詳情
  • 使用說明
  • 常見問題
    • Description
      CatalogueNumber06-340
      BrandFamilyUpstate
      TradeName
      • Upstate
      DescriptionAnti-MycAntibody
      AlternateNames
      • Transcriptionfactorp64
      • avianmyelocytomatosisviraloncogenehomolog
      • mycproto-oncogeneprotein
      • v-mycavianmyelocytomatosisviraloncogenehomolog
      • v-mycmyelocytomatosisviraloncogenehomolog(avian)
      BackgroundInformationc-Myc-,N-Myc-andL-Myc-encodedproteinsfunctionincellproliferation,differentiationandneoplasticdisease.Mycproteinsarenuclearproteinswithrelativelyshorthalflives.Amplificationofthec-Mycgenehasbeenfoundinseveraltypesofhumantumorsincludinglung,breastandcoloncarcinomas,whiletheN-Mycgenehasbeenfoundamplifiedinneuroblastomas.TheL-Mycgenehasbeenreportedtobeamplifiedandexpressedathighlevelinhumansmallcelllungcarcinomas.Thec-Mycproteinisatranscriptionfactor,whichisencodedbythec-Mycgeneonhumanchromosome8q24.c-Myciscommonlyactivatedinavarietyoftumorcellsandplaysanimportantroleincellularproliferation,differentiation,apoptosisandcellcycleprogression.
      ProductInformation
      FormatPurified
      Control
      • EGF-stimulatedA431cells,normalhumancolon,HeLawholecelllysateorJurkatwholecelllysate.
        IncludedPositiveAntigenControl:Catalog#12-302,EGF-stimulatedA431celllysate.Add2.5μLof2-mercaptoethanolper100μLoflysateandboilfor5minutestoreducethepreparation.Load20μgofreducedlysateperlaneforminigels.
      PresentationPurifiedrabbitpolyclonalIgGinbuffercontainingPBS,0.05%sodiumazidewith2mg/mLBSA.Frozensolution.
      StorageandShippingInformation
      StorageConditionsStablefor1yearat-20°Cfromdateofreceipt.

      HandlingRecommendations:
      Uponfirstthaw,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.
      Applications
      ApplicationUseAnti-MycAntibody(rabbitpolyclonalantibody)validatedinChIP,ICC,IP,WBtodetectMycalsoknownasTranscriptionfactorp64,avianmyelocytomatosisviraloncogenehomolog,mycproto-oncogeneprotein.
      KeyApplications
      • Immunocytochemistry
      • Immunoprecipitation
      • WesternBlotting
      • ChromatinImmunoprecipitation(ChIP)
      ApplicationNotesImmunoprecipitation:
      4μgofapreviousantibodyimmuno-precipitatedMycasshownbyanindependentlaboratory.

      Immunocytochemistry:
      Thisantibodyhasbeenusedforimmunocytochemistrybyanindependentlaboratory.(Ohtsuka,T.,1998)
      BIOLOGicalInformation
      ImmunogenBacteriallyexpressedfusion-proteincorrespondingtothefull-lengthhumanMyc.
      ConcentrationPleaserefertotheCertificateofAnalysisforthelot-specificconcentration.
      HostRabbit
      SpecificityRecognizesMycisoformsMr50-67kDa.
      IsotypeIgG
      SpeciesReactivity
      • Human
      • Mouse
      • Avian
      • Xenopus
      SpeciesReactivityNoteStrongestreactivityobservedwithhumanandmouseMyc.Willalsocross-reactwithavianandXenopus.
      AntibodyTypePolyclonalAntibody
      EntrezGeneNumber
      EntrezGeneSummaryTheproteinencodedbythisgeneisamultifunctional,nuclearphosphoproteinthatplaysaroleincellcycleprogression,apoptosisandcellulartransformation.Itfunctionsasatranscriptionfactorthatregulatestranscriptionofspecifictargetgenes.Mutations,overexpression,rearrangementandtranslocationofthisgenehavebeenassociatedwithavarietyofhematopoietictumors,leukemiasandlymphomas,includingBurkittlymphoma.Thereisevidencetoshowthatalternativetranslationinitiationsfromanupstream,in-framenon-AUG(CUG)andadownstreamAUGstartsiteresultintheproductionoftwoisoformswithdistinctN-termini.Thesynthesisofnon-AUGinitiatedproteinissuppressedinBurkitt"slymphomas,suggestingitsimportanceinthenormalfunctionofthisgene.
      GeneSymbol
      • MYC
      • C-MYC
      • c-Myc
      PurificationMethodImmunoaffinityChromatography
      UniProtNumber
      UniProtSummaryFUNCTION:SwissProt:P01106#Participatesintheregulationofgenetranscription.BindsDNAbothinanon-specificmannerandalsospecificallytorecognizesthecoresequence5"-CAC[GA]TG-3".Seemstoactivatethetranscriptionofgrowth-relatedgenes.
      SIZE:439aminoacids;48804Da
      SUBUNIT:EfficientDNAbindingrequiresdimerizationwithanotherbHLHprotein.BindsDNAasaheterodimerwithMAX.InteractswithTAF1CandSPAG9.InteractswithPARP10.InteractswithJARID1AandJARID1B.
      SUBCELLULARLOCATION:Nucleus.
      PTM:PhosphorylatedbyPRKDC.
      DISEASE:SwissProt:P01106#OverexpressionofMYCisimplicatedintheetiologyofavarietyofhematopoietictumors.&AchromosomalaberrationinvolvingMYCmaybeacauseofaformofB-cellchroniclymphocyticleukemia.Translocationt(8;12)(q24;q22)withBTG1.
      SIMILARITY:SwissProt:P01106##Contains1basichelix-loop-helix(bHLH)domain....
      MolecularWeight67kDa
      PhysicochemicalInformation
      Dimensions
      MaterialsInformation
      MaterialsInformation
    售后保障
    螞蟻淘生物188，秉承螞蟻淘一貫的嚴(yán)謹(jǐn)態(tài)度，由螞蟻淘公司專業(yè)人員負(fù)責(zé)品控、采購、物流、銷售、售后，保障正品優(yōu)質(zhì)。以“快速好省，為科研提供好產(chǎn)品、好價(jià)格”為理念，直接鏈接原廠家，從全國各地原制造商嚴(yán)格挑選188款科研精品，剔除品牌溢價(jià)，188生物新電商，把好的產(chǎn)品帶給科研！? 力求給你最優(yōu)質(zhì)的商品。
  • Q：生物188產(chǎn)品正品保障嗎？
    A：生物188質(zhì)量把控人員具有十年的從業(yè)經(jīng)驗(yàn)，在業(yè)界享有良好的口碑；自營商城，直接從廠家采購， 自己的團(tuán)隊(duì)負(fù)責(zé)國際物流和清關(guān)，中間沒有第三方，所有流程嚴(yán)格把控，100%保證正品，假一罰十。

    Q：下單后可以修改訂單嗎？
    A：下單后的商品付款之前可以修改；訂單付款成功，需要聯(lián)系我們客服進(jìn)行修改；客服電話：4000-520-616

    Q：可以開發(fā)票嗎？
    A：本網(wǎng)站所售商品都是正規(guī)清關(guān)，均開具16%正規(guī)發(fā)票，發(fā)票金額含配送費(fèi)金額，另有說明的除外。

    Q：商品幾天可以發(fā)貨？
    A：生物188商品，全部現(xiàn)貨銷售，付款后即可發(fā)貨,一般一周內(nèi)送達(dá)！

    Q：如何聯(lián)系商家？
    A：有任何問題夠可以電話咨詢我們，全國24小時(shí)免費(fèi)服務(wù)熱線：4000-520-616 或聯(lián)系我們的在線客服QQ：1570468124

    Q：收到的商品少了/發(fā)錯了怎么辦？
    A：同個(gè)訂單購買多個(gè)商品可能會分為一個(gè)以上包裹發(fā)出，可能不會同時(shí)送達(dá)，建議查看訂單詳情是否是 部分發(fā)貨狀態(tài)；如未收到，可聯(lián)系在線客服或者致電4000-520-616。

    Q：退換貨/維修需要多長時(shí)間？
    A：一般情況下，退貨處理周期為客戶收到產(chǎn)品一個(gè)月內(nèi)（以快遞公司顯示簽收時(shí)間為準(zhǔn)），包裝規(guī)格、 數(shù)量、品種不符，外觀毀損、短缺或缺陷，請?jiān)谑盏截?4小時(shí)內(nèi)申請退換貨；特殊商品以合同條款為準(zhǔn)。

何為188

極簡而嚴(yán)謹(jǐn)，我們僅銷售188款生物醫(yī)學(xué)科研用品，款款都是爆款；因?yàn)樯偎跃劢?，聚焦甄選每一款產(chǎn)品，聚焦服務(wù)每一位客戶!

關(guān)注我們 :

點(diǎn)擊QQ聯(lián)系我們
生物188微信

關(guān)注188微信公眾號

獲取最新優(yōu)惠活動通知