Immunogen | AsyntheticpeptidecorrespondingtoresiduesinhumanFlotillin-1. |
Clone | EP446Y |
Host | Rabbit |
Specificity | RecognizesHuman,MouseFlotillin-1. |
SpeciesReactivity | |
SpeciesReactivityNote | Human,Mouse(positivecontrol:K562celllysate) |
AntibodyType | MonoclonalAntibody |
EntrezGeneNumber | |
EntrezGeneSummary | Caveolaearesmalldomainsontheinnercellmembraneinvolvedinvesiculartraffickingandsignaltransduction.FLOT1encodesacaveolae-associated,integralmembraneprotein.Thefunctionofflotillin1hasnotbeendetermined. |
GeneSymbol | |
PurificationMethod | ProteinAPurfied |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:O75955#Mayactasascaffoldingproteinwithincaveolarmembranes,functionallyparticipatinginformationofcaveolaeorcaveolae-likevesicles. SIZE:427aminoacids;47355Da SUBUNIT:Hetero-oligomericcomplexofflotillin-1andflotillin-2andcaveolin-1andcaveolin-2(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane,caveola;Peripheralmembraneprotein.Melanosome.Note=Membrane-associatedproteinofcaveolae.IdentifiedbymassspectrometryinmelanosomefractionsfromstageItostageIV. SIMILARITY:SwissProt:O75955##Belongstotheband7/mec-2family.Flotillinsubfamily. |